Coronary Physidogy IFR FFR

iFR (instant wave-Free Ratio)

Unlike FFR, iFR does not require administration of vasodilators because hyperemia is not necessary when measuring pressure during the wave-free period of the cardiac cycle.

iFR is proven to reduce procedure time, patient discomfort and cost compared to FFR.2,3,4

Simplifying workflow

The iFR modality provides a hyperemia-free measurement in as few as five heartbeats.

iFR vs. FFR: same wire, same system, fewer steps

iFR workflow

FFR workflow

Single dichotomous cut-point back by data^2,3

Both DEFINE FLAIR and iFR Swedeheart were designed with the dichotomous cut-point of iFR in the iFR arm. With comparable MACE rates to FFR, these results mean the 0.89 cut-point for iFR is proven and backed by more than 4500 patients of outcome data

FFR (Fractional Flow Reserve)

Philips physiology wires enable measurement of both FFR and iFR, both supported by key industry guidelines including ESC Class IA designation.6

FFR ischemia scale
An FFR lower than 0.75-0.80 is generally considered to be associated with myocardial ischemia.⁷

FFR < 0.75 was validated against the 3 gold standard tests to correlate with ischemia with 100% specificity
FFR between 0.75 and 0.80 may indicate ischemia
FFR > 0.80 is highly likely to be non‑ischemic
AUC guidelines reflect the FAME cutoff of 0.80
(≤ 0.80 Treat, > 0.80 Defer)

Meta Medikal Coronary Physidogy IFR FFR